THE 1949 BARLEY HARVEST

Barley: From Brittle to Stable Harvest

Selection and domestication of plants with genes that prevent grains from shattering in cereals was essential for human civilization's transition to agriculture-based societies. In this issue, Pourkheirandish et al. show that domestication of barley required evolution of a molecular system distinct from other grains, such as rice and maize, and reveal that present-day cultivars derive from two ...

The British Pharmaceutical Codex, 1949

Op-brai150102 1949..1960

Corticocortical interactions between the primary motor cortex, the ventral premotor cortex and posterior parietal motor areas, such as the anterior and caudal intraparietal sulcus, are relevant for skilled voluntary hand function. It remains unclear to what extent these brain regions and their interactions also contribute to basic motor functions after stroke. We hypothesized that white matter ...

Dmd052134 1949..1956

Prediction of clinical efficacy, toxicity, and drug-drug interactions may be improved by accounting for the intracellular unbound drug concentration (Cunbound) in vitro and in vivo. Furthermore, subcellular drug distribution may aid in predicting efficacy, toxicity, and risk assessment. The present study was designed to quantify the intracellular Cunbound and subcellular localization of drugs i...

C3em00214d 1949..1956

Institute of Environmental Systems Barbarastraße 12, D-49076 Osnabrueck, Ge 2 38 64 3668 Department of Biology/Chemistry, Divisio Barbarastraße 13, D-49076 Osnabrueck, Ge Environmental Mineralogy, Institute for Ap Darmstadt, Schnittspahnstr. 9, D-64287 Da † Electronic supplementary informa 10.1039/c3em00214d ‡ Present address: Water, Environment an Recherches Géologiques et Minières (BRG 36009,...